PI3K inhibitor LY294002, Alternatively, reversed this effect of puerarin. Puerarin alleviates migration of mesenchymal-like cells by decreasing MMPs’ protein expression. Puerarin has protective results on H2O2-induced HCAECs EndMT by reducing oxidative pressure, activating the PI3K/Akt pathway, and restricting cell migration. Puerarin provides a
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